Interferon Alfa


- TRADE NAMES: Alferon N; Green-Alpha; Infergen (Intermune); Intron A (Schering); Introna; Introne; Laroferon; Rebetron (Schering); Roceron-A; Roferon-A (Roche)
- INDICATIONS: Chronic hepatitis C virus infection, hairy cell leukemia
- SYNONYM: IFN; INF
- CLASS: Biologic, Immunomodulator, Interferon
- HALF-LIFE: 2 hours
CLINICALLY IMPORTANT, POTENTIALLY HAZARDOUS INTERACTIONS WITH:
Aldesleukin, Amitriptyline, Captopril, Gemfibrozil, Metaxalone, Methadone, Ribavirin, Telbivudine, Theophylline, Theophylline derivatives, Zafirlukast, Zidovudine
PREGNANCY CATEGORY: C
pregnancy category will be X when used in combination with ribavirin
Many of the adverse reactions depend on the nature of the disease being treated. Either hairy cell leukemia [L] or AIDS-related Kaposi’s sarcoma [K].
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SKIN.
HAIR.
NAILS.
MUCOSAL.
CARDIOVASCULAR.
CENTRAL NERVOUS SYSTEM.
ENDOCRINE/METABOLIC.
GASTROINTESTINAL/HEPATIC.
GENITOURINARY.
HEMATOLOGIC.
LOCAL.
NEUROMUSCULAR/SKELETAL.
OCULAR.
OTIC.
RENAL.
RESPIRATORY.
OTHER.
Page last updated 03/30/2023
Symbol key
Incidence 
- <1%
- 1-5%
- 5-10%
- 10-15%
- 15-20%
- 20-30%
- >30%
Warnings in other populations 
- Breast feeding
- Geriatric
- Pediatric