Zafirlukast


- TRADE NAME: Accolate (AstraZeneca)
- INDICATIONS: Asthma
- CLASS: Leukotriene receptor antagonist
- HALF-LIFE: 10 hours
CLINICALLY IMPORTANT, POTENTIALLY HAZARDOUS INTERACTIONS WITH:
Aminophylline, Aspirin, Carvedilol, CYP2C9 substrates, CYP3A4 substrates, Erythromycin, High protein foods, Interferon Alfa, Primidone, Vitamin K antagonists, Warfarin
PREGNANCY CATEGORY: B
Contra-indicated in patients with hepatic impairment including hepatic cirrhosis.
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SKIN.
MUCOSAL.
CENTRAL NERVOUS SYSTEM.
GASTROINTESTINAL/HEPATIC.
NEUROMUSCULAR/SKELETAL.
RESPIRATORY.
OTHER.
Page last updated 08/01/2022
Symbol key
Incidence 
- <1%
- 1-5%
- 5-10%
- 10-15%
- 15-20%
- 20-30%
- >30%
Warnings in other populations 
- Breast feeding
- Geriatric
- Pediatric