Dacarbazine
- TRADE NAMES: Dacatic; Deticene; Detimedac; DTIC; DTIC-Dome (Bayer)
- INDICATIONS: Malignant melanoma, carcinomas
- SYNONYM: DIC
- CLASS: Alkylating agent, Antineoplastic / anticancer agent (see also Immune checkpoint inhibitor)
- HALF-LIFE: 5 hours
CLINICALLY IMPORTANT, POTENTIALLY HAZARDOUS INTERACTIONS WITH:
PREGNANCY CATEGORY: C
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SKIN.
HAIR.
NAILS.
MUCOSAL.
CENTRAL NERVOUS SYSTEM.
ENDOCRINE/METABOLIC.
GASTROINTESTINAL/HEPATIC.
HEMATOLOGIC.
LOCAL.
NEUROMUSCULAR/SKELETAL.
RESPIRATORY.
OTHER.
Page last updated 07/31/2023
Symbol key
Incidence
- <1%
- 1-5%
- 5-10%
- 10-15%
- 15-20%
- 20-30%
- >30%
Warnings in other populations
- Breast feeding
- Geriatric
- Pediatric