Adverse reactions attributed to entire drug class 'Antineoplastic / anticancer agent (see also Immune checkpoint inhibitor)' Please login to view adverse reactions.
Skin[7 reactions]
Flagellate dermatitis
Hyperkeratosis
Hyperpigmentation
Hypersensitivity
Leg ulceration
Photosensitivity
Toxic erythema of chemotherapy (TEC)
(2023): Nguyen CV+, JAMA Dermatol 159(2) , 219-222 (6 cases)(2021): Ríos-Viñuela E+, Acta Derm Venereol 101(4) , adv00429 (45 cases) (localized epidermal necrolysis at the infusion site classified as "localized injection-site TEC")Hair[1 reaction]
Alopecia / hair loss
(2024): Aoyama Y+, Breast Cancer 31(2) , 234-242 (Chemotherapy-Induced Alopecia Distress Scale )(2024): Kraehenbuehl L+, Support Care Cancer 32(6) , 369 (Chemotherapy-Induced Alopecia Distress Scale )(2022): Hrin ML+, J Am Acad Dermatol 86(6) , 1434-1435 [REVIEW](2018): Dunnill CJ+, Oncologist 23(1) , 84-96(2011): Miteva M+, Am J Dermatopathol 33(4) , 345-50 (10 cases)Mucosal[3 reactions] Cardiovascular[5 reactions]
Atrial fibrillation
Bradycardia / sinus bradycardia
Capillary leak syndrome
Cardiomyopathy
Cardiotoxicity
(2025): Chan SHY+, Cancers (Basel) 17(2) , 311 (pharmacovigilance / pharmacoepidemiology) (2024): Jaiswal V+, Medicina (Kaunas) 60(4) , 580 [REVIEW] (cardioprotective benefits associated with concomitant statin therapy)(2023): Qu Y+, Drug Discov Today Sep , Online ahead of print (association)Central Nervous System[4 reactions]
Anosmia (smell loss) / smell disorder
Dysgeusia (taste perversion)
Leukoencephalopathy / posterior reversible encephalopathy syndrome (PRES)
(2024): Lei CL+, Expert Opin Drug Saf Mar , Online ahead of print (pharmacovigilance)Peripheral neuropathy
(2025): Belsky JA+, Support Care Cancer 33(4) , 350 [REVIEW](2025): Jiang J+, Cancer Lett Mar , Online ahead of print [REVIEW](2025): Yanbing L+, World J Surg Oncol 23(1) , 77 [REVIEW](2024): Tao Z+, Cancer Lett Dec , Online ahead of print [REVIEW](2022): Tay N+, Front Mol Biosci Oct (e-Collection) [REVIEW](2021): Hino S+, Ann Maxillofac Surg 11(1) , 86-90 (13 cases)(2021): Hung HW+, Int J Environ Res Public Health 18(11) , 5677(2021): Inoue M+, Sci Rep 11(1) , 11324 [REVIEW](2021): Li T+, Neurol Sci 42(10) , 4109-4121 [REVIEW](2021): Selvy M+, Support Care Cancer 29(7) , 4033-4043(2011): Balayssac D+, Expert Opin Drug Saf 10(3) , 407-17 [REVIEW]Endocrine/Metabolic[1 reaction] Gastrointestinal/Hepatic[8 reactions] Genitourinary[3 reactions]
Gonadotoxicity
Ovarian injury /ovarian damage
(2024): Zha Y+, Zhejiang Da Xue Xue Bao Yi Xue Ban May , Online ahead of print [REVIEW](2011): Hancke K+, Support Care Cancer 19(12) , 1909-19 [REVIEW](2001): Blumenfeld Z, J Soc Gynecol Investig 8(1 Suppl Proceedings) , S60-4(1996): Bines J+, J Clin Oncol 14(5) , 1718-29(1996): Blumenfeld Z+, Hum Reprod 11(8) , 1620-6Ovarian injury /ovarian damage
Hematologic[3 reactions] Ocular[2 reactions] Renal[1 reaction] Respiratory[4 reactions]
Interstitial lung disease / interstitial pneumonitis / interstitial pneumonia (cryptogenic organizing pneumonia) / drug-induced interstitial lung disease
(2025): Hwang IH+, Expert Opin Drug Saf Feb , Online ahead of print [REVIEW] (pharmacovigilance / pharmacoepidemiology) (2024): Jiang T+, Ther Adv Drug Saf Jan (e-Collection) (pharmacovigilance)(2024): Ma Z+, Expert Opin Drug Saf Feb , Online ahead of print [REVIEW](2024): Oishi K+, Respir Med , 107924(2023): Dai HP+, Curr Med Sci 43(1) , 1-12 [REVIEW](2022): Zhonghua Zhong Liu Za Zhi (Chinese) 44(7) , 693-702 [REVIEW](2022): Conte P+, ESMO Open 7(2) , 100404(2022): Miyagahara T+, Asia Pac J Clin Oncol Dec , Online ahead of print6% Pneumonitis
(2024): Oishi K+, Respir Med Dec , Online ahead of print (interstitial lung abnormalities and other associated risk factors)Pulmonary fibrosis
(2024): McCall KL+, Pharmacoepidemiol Drug Saf 33(5) , e5797 (association) (pharmacovigilance / pharmacoepidemiology) Pulmonary toxicity
Other[4 reactions]