Tobramycin
- TRADE NAMES: AKTob Ophthalmic; Oftalmotrisol-T; TOBI (Chiron); Tobra; TobraDex (Alcon); Tobrex
- INDICATIONS: Various serious infections caused by susceptible organisms, superficial ocular infections
- CLASS: Antibiotic, Antibiotic; aminoglycoside, Antimicrobial
- HALF-LIFE: 2–3 hours
CLINICALLY IMPORTANT, POTENTIALLY HAZARDOUS INTERACTIONS WITH:
Adefovir, Aldesleukin, Aminoglycosides, Atracurium, Bumetanide, Daptomycin, Doxacurium, Ethacrynic Acid, Furosemide, Neuromuscular blockers, Pancuronium, Polypeptide antibiotics, Rocuronium, Succinylcholine, Teicoplanin, Torsemide, Vecuronium
PREGNANCY CATEGORY: D
Category D for injection and inhalation; category B for ophthalmic use
Aminoglycosides may cause neurotoxicity and/or nephrotoxicity.
TobraDex is tobramycin and dexamethasone.
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SKIN.
MUCOSAL.
CENTRAL NERVOUS SYSTEM.
GASTROINTESTINAL/HEPATIC.
GENITOURINARY.
OCULAR.
OTIC.
RENAL.
RESPIRATORY.
OTHER.
Page last updated 09/06/2023
Symbol key
Incidence
- <1%
- 1-5%
- 5-10%
- 10-15%
- 15-20%
- 20-30%
- >30%
Warnings in other populations
- Breast feeding
- Geriatric
- Pediatric