Cyclophosphamide
- TRADE NAMES: Cycloblastin; Cyclostin; Cytoxan (Mead Johnson); Endoxan; Endoxana; Genoxal; Ledoxina; Neosar (Gensia); Procytox; Sendoxan
- INDICATIONS: Lymphomas; minimal change nephrotic syndrome in pediatric patients
- SYNONYM: CPM; CTX; CYT
- CLASS: Alkylating agent
- HALF-LIFE: 3–12 hours
CLINICALLY IMPORTANT, POTENTIALLY HAZARDOUS INTERACTIONS WITH:
Aldesleukin, Azathioprine, Belimumab, Clozapine, Cyclopenthiazide, Cyclosporine, Dexamethasone, Etanercept, Itraconazole, Mycophenolate, Pentostatin, Prednisone, Vaccines
PREGNANCY CATEGORY: D
Contra-indicated in patients with urinary outflow obstruction.
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SKIN.
HAIR.
NAILS.
MUCOSAL.
CARDIOVASCULAR.
CENTRAL NERVOUS SYSTEM.
ENDOCRINE/METABOLIC.
GASTROINTESTINAL/HEPATIC.
GENITOURINARY.
HEMATOLOGIC.
LOCAL.
NEUROMUSCULAR/SKELETAL.
RENAL.
RESPIRATORY.
OTHER.
Page last updated 04/28/2023
Symbol key
Incidence 
- <1%
- 1-5%
- 5-10%
- 10-15%
- 15-20%
- 20-30%
- >30%
Seriousness
- Hospitalization possible
- Life threatening
- Fatal
Warnings in other populations
- Breast feeding
- Geriatric
- Pediatric
