Penicillin G drug interactions | Litt's Drug Eruption and Reaction Database

Penicillin G comment watch save

TRADE NAMES: Benzylpenicillin; Crystapen (Britannia); Megacillin; Novopen-G
INDICATIONS: Anthrax, cellulitis, endocarditis, infections, otitis media, rheumatic fever, respiratory infections, septicemia
CLASS: Antibiotic, Antibiotic; beta-lactam, Antibiotic; penicillin, Antimicrobial
HALF-LIFE: 4 hours

CLINICALLY IMPORTANT, POTENTIALLY HAZARDOUS INTERACTIONS WITH:
Estrogens, Imipenem/Cilastatin, Imipenem/Cilastatin, Methotrexate, Minocycline, Phenindione, Probenecid, Sulfinpyrazone, Warfarin

See adverse reactions attributed to class:
Antibiotic
Antibiotic; beta-lactam
Antibiotic; penicillin
Antimicrobial

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Page last updated 07/31/2023

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<1% 1‑5% 5‑10% 10‑15% 15‑20% 20‑30% >30%

Hospitalization possible
Life threatening
Fatal

Breast feeding

Geriatric

Pediatric