Propafenone
- TRADE NAMES: Arythmol; Norfenon; Normorytmin; Rythmex; Rythmol (Reliant); Rytmonorm
- INDICATIONS: Ventricular arrhythmias
- CLASS: Antiarrhythmic, Antiarrhythmic class Ic
- HALF-LIFE: 10–32 hours
CLINICALLY IMPORTANT, POTENTIALLY HAZARDOUS INTERACTIONS WITH:
Amitriptyline, Boceprevir, Carvedilol, Clozapine, Cobicistat/Elvitegravir/Emtricitabine/Tenofovir Alafenamide, Cobicistat/Elvitegravir/Emtricitabine/Tenofovir Disoproxil, Delavirdine, Digoxin, Efavirenz, Fosamprenavir, Grapefruit Juice, Mirabegron, Neostigmine, Paroxetine Hydrochloride, Propranolol, Pyridostigmine, Rifapentine, Ritonavir, Telaprevir, Tipranavir
PREGNANCY CATEGORY: C
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SKIN.
HAIR.
MUCOSAL.
CARDIOVASCULAR.
CENTRAL NERVOUS SYSTEM.
GASTROINTESTINAL/HEPATIC.
HEMATOLOGIC.
LOCAL.
NEUROMUSCULAR/SKELETAL.
RESPIRATORY.
OTHER.
Page last updated 08/02/2021
Symbol key
Incidence 
- <1%
- 1-5%
- 5-10%
- 10-15%
- 15-20%
- 20-30%
- >30%
Seriousness
- Hospitalization possible
- Life threatening
- Fatal
Warnings in other populations
- Breast feeding
- Geriatric
- Pediatric
