Neostigmine bromide is given orally; neostigmine methylsulfate is given parenterally.
Contra-indicated in patients with a previous history of reaction to bromides, or those with peritonitis or mechanical obstruction of the intestinal or urinary tract.
- TRADE NAME: Prostigmin (Valeant)
- INDICATIONS: Myasthenia gravis
- CLASS: Acetylcholinesterase inhibitor, Cholinesterase inhibitor, Parasympathomimetic
- HALF-LIFE: 52 minutes
- CLINICALLY IMPORTANT, POTENTIALLY HAZARDOUS INTERACTIONS WITH:
Aminoglycosides, Antiarrhythmics, Anticholinergics, Chloroquine, Clindamycin, Hydroxychloroquine, Kanamycin, Lithium, Local and general anesthetics, Neomycin, Non-depolarising muscle relaxants, Polymixins, Propafenone, Propranolol, Streptomycin, Succinylcholine - PREGNANCY: Anticholinesterase drugs may cause uterine irritability and induce premature labor when given intravenously to pregnant women near term
- See adverse reactions attributed to class:
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Page last updated 10/11/2024
