• TRADE NAME: Bevyxxa (Portola)
  • INDICATIONS: Prophylaxis of venous thromboembolism in adult patients hospitalized for an acute medical illness who are at risk for thromboembolic complications
  • CLASS: Direct factor Xa inhibitor
  • HALF-LIFE: 19–27 hours
  • FDA APPROVAL DATE: 06/23/2017
  • CLINICALLY IMPORTANT, POTENTIALLY HAZARDOUS INTERACTIONS WITH:
    Amiodarone, Anticoagulants, antiplatelet drugs and thrombolytics, Azithromycin, Clarithromycin, Ketoconazole, Verapamil
  • PREGNANCY: Likely to increase the risk of hemorrhage during pregnancy and delivery

Contra-indicated in patients with active pathological bleeding.

SPINAL/EPIDURAL HEMATOMA

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Page last updated 07/31/2023

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Incidence

<1% 1‑5% 5‑10% 10‑15% 15‑20% 20‑30% >30%

Seriousness

Hospitalization possible
Life threatening
Fatal

Warnings in other populations

BreastfeedingBreast feeding

GeriatricGeriatric

PediatricPediatric