Rituximab-Abbs (Truxima) is a biosimilar to Rituximab (Rituxan). Approved 11/28/2018
Rituximab-pvvr (Ruxience) is a biosimilar to Rituximab (Rituxan). Approved 07/23/2019
Rituximab-arrx (Riabni) is a biosimilar to Rituximab (Rituxan). Approved 12/17/2020
- TRADE NAMES: MabThera (Roche); Rituxan (Genentech)
- INDICATIONS: Non-Hodgkin’s lymphoma, chronic lymphocytic leukemia, rhematoid arthritis (in combination with methotrexate), granulomatosis with polyangiitis and mycroscopic polyangiitis (in combination with glucocorticoids)
- CLASS: Biologic, Biologic disease-modifying antirheumatic drug (bDMARD), CD20-directed cytolytic monoclonal antibody, Disease-modifying antirheumatic drug (DMARD), Immunosuppressant, Monoclonal antibody
- HALF-LIFE: 60 hours (after first infusion)
- FDA APPROVAL DATE: 11/26/1997
- CLINICALLY IMPORTANT, POTENTIALLY HAZARDOUS INTERACTIONS WITH:
Benazepril, Captopril, Certolizumab, Cisplatin, Clevidipine, Enalapril, Fosinopril, Irbesartan, Lisinopril, Olmesartan, Quinapril, Ramipril
- See adverse reactions attributed to class:
Biologic disease-modifying antirheumatic drug (bDMARD)
FATAL INFUSION REACTIONS, SEVERE MUCOCUTANEOUS REACTIONS, HEPATITIS B VIRUS REACTIVATION and PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY
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Click on the DRUG REVIEW ARTICLE tab (above) to see a review of rituximab in the Taylor & Francis journal Expert Opinion on Drug Safety.
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Page last updated 01/13/2025
