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Tekamlo is aliskiren and amlodipine; Tekturna HCT is aliskiren and hydrochlorothiazide; Valturna is aliskiren and valsartan.
Hydrochlorothiazide is a sulfonamide and can be absorbed systemically. Sulfonamides can produce severe, possibly fatal, reactions such as toxic epidermal necrolysis and Stevens-Johnson syndrome.
Contra-indicated for concomitant use with angiotensin receptor blockers or angiotensin-converting enzyme (ACE) inhibitors in patients with diabetes.
FETAL TOXICITY
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