Ubrogepant
- TRADE NAME: Ubrelvy (Allergan)
- INDICATIONS: Acute treatment of migraine with or without aura in adults
- CLASS: Calcitonin gene-related peptide (CGRP) receptor antagonist
- HALF-LIFE: ~5–7 hours
FDA APPROVAL DATE: 12/23/2019
CLINICALLY IMPORTANT, POTENTIALLY HAZARDOUS INTERACTIONS WITH:BCRP and/or P-gp only inhibitors, CYP3A4 inhibitors, CYP3A4 inducers, Ciprofloxacin, Clarithromycin, Cyclosporine, Fluconazole, Fluvoxamine, Grapefruit Juice, Itraconazole, Ketoconazole, Phenytoin, Rifampin, St John's Wort, Verapamil
There are no adequate data on the developmental risk associated with use in pregnant women.
Ubrogepant is not indicated for the preventive treatment of migraine.
Avoid use in patients with end-stage renal disease.
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MUCOSAL.
CENTRAL NERVOUS SYSTEM.
ENDOCRINE/METABOLIC.
GASTROINTESTINAL/HEPATIC.
NEUROMUSCULAR/SKELETAL.
RESPIRATORY.
Page last updated 08/01/2022
Symbol key
Incidence 
- <1%
- 1-5%
- 5-10%
- 10-15%
- 15-20%
- 20-30%
- >30%
Warnings in other populations 
- Breast feeding
- Geriatric
- Pediatric