Bexarotene
- TRADE NAME: Targretin (Eisai)
- INDICATIONS: Cutaneous T-cell lymphoma, mycosis fungoides
- CLASS: Antineoplastic / anticancer agent (see also Immune checkpoint inhibitor), Retinoid
- HALF-LIFE: 7 hours
CLINICALLY IMPORTANT, POTENTIALLY HAZARDOUS INTERACTIONS WITH:
Acitretin, Atorvastatin, Beta-Carotene, Carboplatin, Conivaptan, Dexamethasone, Dong Quai, Gemfibrozil, Grapefruit Juice, Isotretinoin, Oral Contraceptives, Paclitaxel, Saxagliptin, St John's Wort, Tamoxifen, Tetracyclines, Tretinoin, Vitamin A
PREGNANCY CATEGORY: X
Retinoids can cause birth defects, and women should avoid bexarotene when pregnant or trying to conceive.
AVOID IN PREGNANCY
See full prescribing information for complete boxed warning.
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SKIN.
HAIR.
MUCOSAL.
CENTRAL NERVOUS SYSTEM.
ENDOCRINE/METABOLIC.
GASTROINTESTINAL/HEPATIC.
HEMATOLOGIC.
NEUROMUSCULAR/SKELETAL.
RENAL.
RESPIRATORY.
OTHER.
Page last updated 07/31/2023
Symbol key
Incidence 
- <1%
- 1-5%
- 5-10%
- 10-15%
- 15-20%
- 20-30%
- >30%
Seriousness
- Hospitalization possible
- Life threatening
- Fatal
Warnings in other populations
- Breast feeding
- Geriatric
- Pediatric
