Valganciclovir is rapidly converted to ganciclovir in the body.
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- TRADE NAME: Valcyte (Roche)
- INDICATIONS: Cytomegalovirus retinitis (CMV) in patients with AIDS, prevention of CMV disease in high-risk transplant patients
- CLASS: Antiviral, Guanine nucleoside analog
- HALF-LIFE: 4 hours (in severe renal impairment up to 68%)
- CLINICALLY IMPORTANT, POTENTIALLY HAZARDOUS INTERACTIONS WITH:
Abacavir, Cobicistat/Elvitegravir/Emtricitabine/Tenofovir Alafenamide, Cobicistat/Elvitegravir/Emtricitabine/Tenofovir Disoproxil, Emtricitabine, Tenofovir Disoproxil - PREGNANCY: May cause fetal toxicity based on findings in animal studies
- See adverse reactions attributed to class:
HEMATOLOGIC TOXICITY, IMPAIRMENT OF FERTILITY, FETAL TOXICITY, MUTAGENESIS AND CARCINOGENESIS
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Page last updated 07/31/2023
