Perampanel
- TRADE NAME: Fycompa (Eisai)
- INDICATIONS: Partial-onset seizures, primary generalized tonic-clonic seizures
- CLASS: AMPA glutamate receptor antagonist, Anticonvulsant, Antiepileptic
- HALF-LIFE: ~105 hours
CLINICALLY IMPORTANT, POTENTIALLY HAZARDOUS INTERACTIONS WITH:
Alcohol, Carbamazepine, Oral Contraceptives, Oxcarbazepine, Phenobarbital, Phenytoin, Primidone, Rifampin, St John's Wort
PREGNANCY CATEGORY: C
SERIOUS PSYCHIATRIC AND BEHAVIORAL REACTIONS
See full prescribing information for complete boxed warning.
Please login to see the rest of this drug profile
SKIN.
HAIR.
MUCOSAL.
CENTRAL NERVOUS SYSTEM.
ENDOCRINE/METABOLIC.
GASTROINTESTINAL/HEPATIC.
HEMATOLOGIC.
NEUROMUSCULAR/SKELETAL.
OCULAR.
RESPIRATORY.
OTHER.
Click on the DRUG REVIEW ARTICLE tab (above) to see a review of perampanel in the Taylor & Francis journal Expert Opinion on Drug Safety. (Note that non-subscribers to the journal will only be able to see an abstract of the article.)
Page last updated 09/05/2023
Symbol key
Incidence 
- <1%
- 1-5%
- 5-10%
- 10-15%
- 15-20%
- 20-30%
- >30%
Seriousness
- Hospitalization possible
- Life threatening
- Fatal
Warnings in other populations
- Breast feeding
- Geriatric
- Pediatric
