Oxaliplatin

BreastfeedingPediatric
  • TRADE NAMES: Eloxatin (Sanofi-Aventis); Heloxatin
  • INDICATIONS:

    Metastatic carcinoma of the colon or rectum (in combination with fluorouracil/leucovorin (FOLFOX))

    Advanced pancreatic cancer (in combination with irinotecan/fluorouracil/leucovorin (FOLFIRINOX or FOLFOXIRI))

     


  • CLASS: Alkylating agent, Antineoplastic, Platinum-based antineoplastic
  • HALF-LIFE: 391 hours
CLINICALLY IMPORTANT, POTENTIALLY HAZARDOUS INTERACTIONS WITH:

Aminoglycosides, BCG Vaccine, Capreomycin, Cardiac glycosides, Clozapine, Denosumab, Diuretics, Leflunomide, Natalizumab, Pimecrolimus, Polymyxins, Sipuleucel-T, Tacrolimus, Taxanes, Topotecan, Trastuzumab, Vaccines, Vitamin K antagonists

PREGNANCY CATEGORY: D

ANAPHYLACTIC REACTIONS

See full prescribing information for complete boxed warning.

Our database has 157 adverse reactions for this drug across the following areas

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SKIN.
HAIR.
NAILS.
MUCOSAL.
CARDIOVASCULAR.
CENTRAL NERVOUS SYSTEM.
ENDOCRINE/METABOLIC.
GASTROINTESTINAL/HEPATIC.
GENITOURINARY.
HEMATOLOGIC.
LOCAL.
NEUROMUSCULAR/SKELETAL.
OCULAR.
RENAL.
RESPIRATORY.
OTHER.


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Click on the DRUG REVIEW ARTICLE tab (above) to see a review of oxaliplatin in the Taylor & Francis journal Expert Opinion on Drug Safety. (Note that non-subscribers to the journal will only be able to see an abstract of the article.)

Page last updated 03/23/2020

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Incidence info

  • <1%
  • 1-5%
  • 5-10%
  • 10-15%
  • 15-20%
  • 20-30%
  • >30%

Seriousness info

  • Hospitalization possible
  • Life threatening
  • Fatal

Warnings in other populations info

  • Breast feeding
  • Geriatric
  • Pediatric
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