Sodium Oxybate


- TRADE NAME: Xyrem (Jazz)
- INDICATIONS: Cataplexy (in patients with narcolepsy)
- SYNONYM: GHB
- CLASS: Anesthetic; general
- HALF-LIFE: 0.3–1 hour
Alcohol, Amitriptyline, Antipsychotics, Benzodiazepines, Clobazam, Hydromorphone, Hypnotics, Levomepromazine, Phenobarbital, Risperidone, Sedatives, Tricyclic depressants, Zuclopenthixol
PREGNANCY CATEGORY: B
Sodium oxybate is a class of drugs that are also known as: designer drugs, party drugs, club drugs, recreational drugs, rave drugs, fantasy drugs, date rape drugs or abuse drugs.
See full prescribing information for complete boxed warning.
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Click on the DRUG REVIEW ARTICLE tab (above) to see a review of sodium oxybate in the Taylor & Francis journal Expert Opinion on Drug Safety. (Note that non-subscribers to the journal will only be able to see an abstract of the article.)
Page last updated 07/31/2023
Symbol key
Incidence 
- <1%
- 1-5%
- 5-10%
- 10-15%
- 15-20%
- 20-30%
- >30%
Warnings in other populations 
- Breast feeding
- Geriatric
- Pediatric