Timolol
- TRADE NAMES: Apo-Timol; Aquanil; Betimol; Blocadren (Merck); Cosopt (Merck); Dispatim; Nu-Timolol; Tenopt; Tiloptic; Timacor; Timolide (Merck); Timoptic (Merck); Timoptol
- INDICATIONS: Hypertension
- CLASS: Adrenergic beta-receptor antagonist
- HALF-LIFE: 2–2.7 hours
Clonidine, Cobicistat/Elvitegravir/Emtricitabine/Tenofovir Alafenamide, Cobicistat/Elvitegravir/Emtricitabine/Tenofovir Disoproxil, Epinephrine, Ergot, Prednisone, Verapamil
PREGNANCY CATEGORY: C
Cosopt is timolol and dorzolamide; Timolide is timolol and hydrochlorothiazide. Dorzolamide and hydrochlorothiazide are sulfonamides and can be absorbed systemically. Sulfonamides can produce severe, possibly fatal, reactions such as toxic epidermal necrolysis and Stevens-Johnson syndrome.
Cutaneous side-effects of beta-receptor blockers are clinically polymorphous. They apparently appear after several months of continuous therapy.
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Click on the DRUG REVIEW ARTICLE tab (above) to see a review of ophthalmic timolol in the Taylor & Francis journal Expert Opinion on Drug Safety. (Note that non-subscribers to the journal will only be able to see an abstract of the article.)
Page last updated 03/31/2022
Symbol key
Incidence 
- <1%
- 1-5%
- 5-10%
- 10-15%
- 15-20%
- 20-30%
- >30%
Seriousness
- Hospitalization possible
- Life threatening
- Fatal
Warnings in other populations
- Breast feeding
- Geriatric
- Pediatric
