• FDA APPROVAL DATE: 01/07/2022
  • CLINICALLY IMPORTANT, POTENTIALLY HAZARDOUS INTERACTIONS WITH:
    CYP3A4 inducers, CYP3A4 inhibitors, Diltiazem, Efavirenz, Itraconazole, Ranitidine, Ranitidine, Rifampin
  • PREGNANCY: No available data on daridorexant use in pregnant women to evaluate for drug-associated risks of major birth defects, miscarriage, or other adverse maternal or fetal outcomes.

CNS-Depressant Effects and Daytime Impairment: Impairs alertness and motor coordination including morning impairment. Risk increases when used with other central nervous system depressants. Avoid alcohol consumption with daridorexant.

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Page last updated 07/18/2024

Symbol key

Incidence

<1% 1‑5% 5‑10% 10‑15% 15‑20% 20‑30% >30%

Seriousness

Hospitalization possible
Life threatening
Fatal

Warnings in other populations

BreastfeedingBreast feeding

GeriatricGeriatric

PediatricPediatric