• FDA APPROVAL DATE: 04/17/2020
  • CLINICALLY IMPORTANT, POTENTIALLY HAZARDOUS INTERACTIONS WITH:
    CYP2C8 Inducers, CYP2C8 Inhibitors, CYP3A Inducers, CYP3A Substrates, CYP3A Substrates, Digoxin, Gemfibrozil, Itraconazole, Metformin, Midazolam, P-gp Substrates, Repaglinide, Rifampin
  • PREGNANCY: Tucatinib can cause fetal harm when administered to a pregnant woman. Advise pregnant women and females of reproductive potential of the potential risk to the fetus.

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Page last updated 08/21/2024

Symbol key

Incidence

<1% 1‑5% 5‑10% 10‑15% 15‑20% 20‑30% >30%

Seriousness

Hospitalization possible
Life threatening
Fatal

Warnings in other populations

BreastfeedingBreast feeding

GeriatricGeriatric

PediatricPediatric