Fosamprenavir
- TRADE NAME: Lexiva (ViiV)
- INDICATIONS: HIV infections (in combination with other antiretrovirals)
- CLASS: Antiretroviral, HIV-1 protease inhibitor
- HALF-LIFE: 7.7 hours
Amiodarone, Atorvastatin, Avanafil, Bepridil, Carbamazepine, Darifenacin, Delavirdine, Dihydroergotamine, Efavirenz, Etravirine, Flecainide, Flibanserin, Itraconazole, Ketoconazole, Lidocaine, Lopinavir, Lovastatin, Midazolam, Mifepristone, Nevirapine, Olaparib, Phenobarbital, Phenytoin, Pimozide, Posaconazole, Propafenone, Quinidine, Quinine, Rifabutin, Rifampin, Rilpivirine, Ritonavir, Rivaroxaban, Rosuvastatin, Sildenafil, Simeprevir, Simvastatin, St John's Wort, Tadalafil, Telaprevir, Telithromycin, Tipranavir, Triazolam, Vardenafil, Warfarin
PREGNANCY CATEGORY: C
Fosamprenavir is a sulfonamide and can be absorbed systemically. Sulfonamides can produce severe, possibly fatal, reactions such as toxic epidermal necrolysis and Stevens-Johnson syndrome.
Fosamprenavir is a prodrug of amprenavir (see separate entry).
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Page last updated 07/31/2023
Symbol key
Incidence
- <1%
- 1-5%
- 5-10%
- 10-15%
- 15-20%
- 20-30%
- >30%
Warnings in other populations
- Breast feeding
- Geriatric
- Pediatric