Carbamazepine

CLINICALLY IMPORTANT, POTENTIALLY HAZARDOUS INTERACTIONS WITH:

Abiraterone, Acetaminophen, Acetylcysteine, Adenosine, Afatinib, Amitriptyline, Amlodipine, Amprenavir, Apixaban, Apremilast, Aprepitant, Aripiprazole, Artemether/Lumefantrine, Bictegravir/Emtricitabine/Tenofovir Alafenamide, Boceprevir, Brigatinib, Brivaracetam, Buprenorphine, Cabazitaxel, Cabozantinib, Caffeine, Caspofungin, Cefixime, Ceritinib, Charcoal, Citalopram, Clarithromycin, Clobazam, Clopidogrel, Clorazepate, Clozapine, Cobicistat/Elvitegravir/Emtricitabine/Tenofovir Disoproxil, Cobimetinib, Copanlisib, Crizotinib, Dabigatran, Daclatasvir, Darunavir, Dasabuvir/Ombitasvir/Paritaprevir/Ritonavir, Dasatinib, Deflazacort, Delavirdine, Dexamethasone, Diltiazem, Doxacurium, Doxycycline, Dronedarone, Efavirenz, Elbasvir & Grazoprevir, Eliglustat, Emtricitabine/Rilpivirine/Tenofovir Alafenamide, Enzalutamide, Erythromycin, Eslicarbazepine, Estradiol, Ethosuximide, Etravirine, Ezogabine, Felodipine, Fesoterodine, Flibanserin, Fosamprenavir, Gefitinib, Glecaprevir & Pibrentasvir, Ibrutinib, Idelalisib, Imatinib, Indinavir, Influenza Vaccine, Isavuconazonium Sulfate, Isotretinoin, Itraconazole, Ixabepilone, Ixazomib, Lacosamide, Lapatinib, Ledipasvir & Sofosbuvir, Lesinurad, Levetiracetam, Levomepromazine, Levonorgestrel, Linezolid, Lopinavir, Methylprednisolone, Midazolam, Midostaurin, Mifepristone, Naldemedine, Nelfinavir, Neratinib, Nevirapine, Nifedipine, Nilotinib, Nintedanib, Olanzapine, Olaparib, Ombitasvir/Paritaprevir/Ritonavir, Ondansetron, Osimertinib, Oxcarbazepine, Oxtriphylline, Paclitaxel, Palbociclib, Paliperidone, Perampanel, Pimavanserin, Piracetam, Ponatinib, Prednisolone, Propoxyphene, Regorafenib, Rilpivirine, Riociguat, Risperidone, Ritonavir, Rivaroxaban, Roflumilast, Romidepsin, Rufinamide, Simeprevir, Simvastatin, Sodium Picosulfate, Sofosbuvir, Sofosbuvir & Velpatasvir, Sofosbuvir/Velpatasvir/Voxilaprevir, Solifenacin, Sonidegib, Sorafenib, St John's Wort, Sunitinib, Telaprevir, Telithromycin, Temsirolimus, Tenofovir Alafenamide, Terbinafine, Tezacaftor/Ivacaftor, Thalidomide, Tiagabine, Ticagrelor, Tipranavir, Tolvaptan, Tramadol, Triamcinolone, Troleandomycin, Ulipristal, Valbenazine, Vandetanib, Vemurafenib, Venetoclax, Verapamil, Vorapaxar, Voriconazole, Vortioxetine, Ziprasidone, Zuclopenthixol

PREGNANCY CATEGORY: D

Carbamazepine is the main cause of Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), and the hypersensitivity syndrome in Han Chinese, and in peoples of other Southeast Asian countries, as a result of a strong pharmacogenetic association that has been reported in these patients between the human leukocyte antigen (HLA)-B*1502 and carbamazepine.

SERIOUS DERMATOLOGIC REACTIONS AND HLA-B*1502 ALLELE; APLASTIC ANEMIA AND AGRANULOCYTOSIS


See full prescribing information for complete boxed warning.

Our database has 159 adverse reactions for this drug across the following areas

Please login to see the rest of this drug profile


Not a subscriber? Click here to subscribe

SKIN
HAIR
NAILS
MUCOSAL
CARDIOVASCULAR
CENTRAL NERVOUS SYSTEM
NEUROMUSCULAR/SKELETAL
GASTROINTESTINAL/HEPATIC
RESPIRATORY
ENDOCRINE/METABOLIC
GENITOURINARY
RENAL
HEMATOLOGIC
OTIC
OCULAR
OTHER


Page last updated 07/19/2018

Drug Eruption Mobile Site

Symbol key

Incidence info

  • <1%
  • 1-5%
  • 5-10%
  • 10-15%
  • 15-20%
  • 20-30%
  • >30%

Seriousness info

  • Hospitalization possible
  • Life threatening
  • Fatal

Warnings in other populations info

  • Breast feeding
  • Geriatric
  • Pediatric