Rifampin

  • TRADE NAMES: Abrifam; Corifam; Ramicin; Rifadin (Sanofi-Aventis); Rifaldin; Rifamed; Rimactane (Novartis); Rimpin; Rimycin; Rofact
  • INDICATIONS: Tuberculosis
  • SYNONYM: rifampicin
  • CLASS: Antibiotic, rifamycin, CYP1A2 inducer, CYP3A4 inducer
  • HALF-LIFE: 3–5 hours
CLINICALLY IMPORTANT, POTENTIALLY HAZARDOUS INTERACTIONS WITH:

Abacavir, Abiraterone, Acalabrutinib, Afatinib, Amiodarone, Amprenavir, Anisindione, Antacids, Anticoagulants, Apixaban, Apremilast, Aprepitant, Artemether/Lumefantrine, Atazanavir, Atorvastatin, Atovaquone, Atovaquone/Proguanil, Beclomethasone, Bedaquiline, Betamethasone, Bictegravir/Emtricitabine/Tenofovir Alafenamide, Bisoprolol, Boceprevir, Bosentan, Brentuximab Vedotin, Brigatinib, Brivaracetam, Buprenorphine, Cabazitaxel, Cabozantinib, Canagliflozin, Caspofungin, Ceritinib, Clobazam, Clozapine, Cobimetinib, Copanlisib, Corticosteroids, Cortisone, Crizotinib, Cyclosporine, Cyproterone, Dabigatran, Daclatasvir, Dapsone, Darunavir, Dasabuvir/Ombitasvir/Paritaprevir/Ritonavir, Dasatinib, Deferasirox, Deflazacort, Delavirdine, Dexamethasone, Diclofenac, Dicumarol, Digoxin, Doxycycline, Dronedarone, Edoxaban, Efavirenz, Elbasvir & Grazoprevir, Eliglustat, Eluxadoline, Emtricitabine/Rilpivirine/Tenofovir Alafenamide, Enzalutamide, Estradiol, Eszopiclone, Etoricoxib, Etravirine, Everolimus, Fesoterodine, Flibanserin, Fludrocortisone, Flunisolide, Fosamprenavir, Gadoxetate, Gefitinib, Gestrinone, Glecaprevir & Pibrentasvir, Halothane, Hydrocortisone, Ibrutinib, Idelalisib, Imatinib, Indinavir, Isavuconazonium Sulfate, Isoniazid, Itraconazole, Ixabepilone, Ixazomib, Ketoconazole, Lapatinib, Ledipasvir & Sofosbuvir, Leflunomide, Lesinurad, Letermovir, Levodopa, Levonorgestrel, Linagliptin, Linezolid, Lopinavir, Lorcainide , Losartan, Lumacaftor/Ivacaftor, Lurasidone, Macitentan, Maraviroc, Methylprednisolone, Midazolam, Midostaurin, Mifepristone, Naldemedine, Nelfinavir, Neratinib, Netupitant & Palonosetron, Nevirapine, Nifedipine, Nilotinib, Olaparib, Ombitasvir/Paritaprevir/Ritonavir, Ondansetron, Oral Contraceptives, Osimertinib, Ospemifene, Oxtriphylline, Paclitaxel, Palbociclib, Pazopanib, Perampanel, Phenylbutazone, Pimavanserin, Pioglitazone, Pitavastatin, Pomalidomide, Ponatinib, Praziquantel, Prednisolone, Prednisone, Propranolol, Propyphenazone, Protease inhibitors, Pyrazinamide, Quinine, Raltegravir, Ramelteon, Ranolazine, Regorafenib, Ribociclib, Rilpivirine, Riociguat, Ritonavir, Rivaroxaban, Roflumilast, Romidepsin, Rosiglitazone, Saquinavir, Simeprevir, Simvastatin, Sofosbuvir, Sofosbuvir & Velpatasvir, Sofosbuvir/Velpatasvir/Voxilaprevir, Solifenacin, Sonidegib, Sorafenib, Sunitinib, Tacrolimus, Tadalafil, Tasimelteon, Telaprevir, Telithromycin, Temsirolimus, Tenofovir Alafenamide, Terbinafine, Tezacaftor/Ivacaftor, Thalidomide, Ticagrelor, Tipranavir, Tofacitinib, Tolvaptan, Trabectedin, Treprostinil, Triamcinolone, Triazolam, Trimethoprim, Troleandomycin, Ulipristal, Valbenazine, Vandetanib, Vemurafenib, Venetoclax, Vorapaxar, Voriconazole, Vortioxetine, Warfarin, Zaleplon, Zidovudine, Zolpidem

PREGNANCY CATEGORY: C

Our database has 91 adverse reactions for this drug across the following areas

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SKIN
HAIR
MUCOSAL
CARDIOVASCULAR
CENTRAL NERVOUS SYSTEM
NEUROMUSCULAR/SKELETAL
GASTROINTESTINAL/HEPATIC
RESPIRATORY
ENDOCRINE/METABOLIC
GENITOURINARY
RENAL
HEMATOLOGIC
OCULAR
LOCAL
OTHER


Page last updated 09/19/2018

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Incidence info

  • <1%
  • 1-5%
  • 5-10%
  • 10-15%
  • 15-20%
  • 20-30%
  • >30%

Seriousness info

  • Hospitalization possible
  • Life threatening
  • Fatal

Warnings in other populations info

  • Breast feeding
  • Geriatric
  • Pediatric