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class – HMG-CoA reductase inhibitor / statin – 8 items found

Adverse reactions attributed to entire drug class 'HMG-CoA reductase inhibitor / statin'

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Neurological adverse effect / neurological deficit

    • (2024): Li J+, Endocr Metab Immune Disord Drug Targets Oct, Online ahead of print (association) (pharmacovigilance / pharmacoepidemiology)

Neuromyopathy

Hepatotoxicity / liver injury / acute liver injury / drug-induced liver injury (DILI)

    • (2023): Su FY+, Horm Metab Res Nov, Online ahead of print (with concomitant medication)

Myalgia/Myositis/Myopathy/Myotoxicity

Myasthenia gravis

    • (2023): Drug Ther Bull Dec, Online ahead of print (UK MHRA; September 2023; Statins: very infrequent reports of myasthenia gravis. Globally, there has been a very small number of reports of new-onset or aggravation of pre-existing myasthenia gravis with atorvastatin, pravastatin, lovastatin, fluvastatin, simvastatin, rosuvastatin and pitavastatin (single-ingredient and fixed-dose combination products). Advise patients taking statins to be alert to new symptoms for myasthenia gravis, or worsening symptoms of pre-existing myasthenia gravis, and to seek medical advice if these occur.)

Necrotizing myopathy / immune-mediated necrotizing myopathy

Rhabdomyolysis

Ocular adverse effect