Litts Drug Eruption & Reaction Database - Presented by CRC Press

The most comprehensive database on adverse drug reactions for our profession.David Adams MD


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Drugs belonging to  restart save

class – HMG-CoA reductase inhibitor / statin – 8 items found

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Atorvastatin

Fluvastatin

Lovastatin

Pitavastatin

Pravastatin

Red Rice Yeast

Rosuvastatin

Simvastatin


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Adverse reactions attributed to entire drug class 'HMG-CoA reductase inhibitor / statin'

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Neurological adverse effect / neurological deficit

    • (2024): Li J+, Endocr Metab Immune Disord Drug Targets Oct, Online ahead of print (association) (pharmacovigilance / pharmacoepidemiology)

Neuromyopathy

    • (2022): Attardo S+, Int J Mol Sci 23(15), 8364 [REVIEW]

Hepatotoxicity / liver injury / acute liver injury / drug-induced liver injury (DILI)

    • (2023): Su FY+, Horm Metab Res Nov, Online ahead of print (with concomitant medication)

Myalgia/Myositis/Myopathy/Myotoxicity

    • (2025): Sridharan K+, Curr Rev Clin Exp Pharmacol Mar, Online ahead of print [REVIEW] (pharmacogenomics)
    • (2023): Wei C+, J Clin Med 12(10), 3548 (with daptomycin; association)
    • (2023): Yow HY+, Asian Biomed (Res Rev News) 17(3), 95-114 [REVIEW] (pharmacogenomics)

Myasthenia gravis

    • (2023): Drug Ther Bull Dec, Online ahead of print (UK MHRA; September 2023; Statins: very infrequent reports of myasthenia gravis. Globally, there has been a very small number of reports of new-onset or aggravation of pre-existing myasthenia gravis with atorvastatin, pravastatin, lovastatin, fluvastatin, simvastatin, rosuvastatin and pitavastatin (single-ingredient and fixed-dose combination products). Advise patients taking statins to be alert to new symptoms for myasthenia gravis, or worsening symptoms of pre-existing myasthenia gravis, and to seek medical advice if these occur.)

Necrotizing myopathy / immune-mediated necrotizing myopathy

    • (2022): Somagutta MKR+, Reumatologia 60(1), 63-69 [REVIEW]
    • (2017): Tiniakou E+, Curr Opin Rheumatol 29(6), 604-611 [REVIEW]

Rhabdomyolysis

    • (2022): Kunakorntham P+, BMC Med Inform Decis Mak 22(1), 233

Ocular adverse effect

    • (2015): Bahrami B+, Med J Aust 203(9), 365 [REVIEW]
    • (2015): Mizranita V+, Int J Clin Pharm 37(5), 844-50 [REVIEW]

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