Litts Drug Eruption & Reaction Database - Presented by CRC Press

Nothing else can remotely compare to it.Patricia Wong, MD, Stanford University Medical Centre


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Drugs belonging to  restart save

class – Analgesic; opioid – 5 items found

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Alfentanil

Dihydrocodeine

Fentanyl

Meptazinol

Tapentadol


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Adverse reactions attributed to entire drug class 'Analgesic; opioid'

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Pruritus (itching)

    • (2015): Benson JL+, Consult Pharm 30(4), 221

Cardiovascular adverse effect (includes major adverse cardiovascular events (MACE))

    • (2023): Sherbini AE+, Trends Cardiovasc Med Apr, Online ahead of print [REVIEW]

CNS depression

    • (2022): Hahn J+, Front Pharmacol Oct (e-Collection) [REVIEW] (with gabapentinoid co-administration)

Delirium

    • (2023): Hiratsuka Y+, Support Care Cancer 31(12), 6326%
    • (2022): Raso J+, Int J Clin Pharm Jan, Online ahead of print (association)

Encephalopathy (includes hepatic encephalopathy)

    • (2016): Soleimanpour H+, Hepat Mon 16(4), Epub [REVIEW]

Hallucinations

    • (2016): Sivanesan E+, Anesth Analg 123(4), 836 [REVIEW]

Sedation

    • (2016): Soleimanpour H+, Hepat Mon 16(4), Epub [REVIEW]

Serotonin syndrome

    • (2015): Zadori D+, Expert Opin Drug Saf 14(6), 877 [REVIEW]

Somnolence (drowsiness)

    • (2023): Hiratsuka Y+, Support Care Cancer 31(12), 6325%
    • (2021): Tanaka R+, Medicine (Baltimore) 100(44), e27565 (genotype correlation)

Endocrine-related adverse effect / endocrinopathy

    • (2021): Medina II WA+, Jul [REVIEW]

Hypogonadism (includes androgen deficiency)

    • (2025): Kafel H+, Andrology Feb, Online ahead of print [REVIEW]

Constipation

    • (2025): Boilève A+, Bull Cancer (French) Feb, Online ahead of print [REVIEW]
    • (2023): Hiratsuka Y+, Support Care Cancer 31(12), 6325%
    • (2022): Alvaro D+, Pain Ther Feb, Online ahead of print [REVIEW]
    • (2018): Bhimji SS+, StatPearls Mar, Epub
    • (2016): Soleimanpour H+, Hepat Mon 16(4), Epub [REVIEW]
    • (2015): Nelson AD+, Therap Adv Gastroenterol 8(4), 206 [REVIEW]
    • (2015): Sani H+, Consult Pharm 30(10), 61280%Geriatric

Nausea

    • (2024): Kang Y+, Int J Mol Sci 25(16), 8845 (pharmacogenomics)
    • (2023): Hiratsuka Y+, Support Care Cancer 31(12), 6325%

Vomiting

    • (2023): Hiratsuka Y+, Support Care Cancer 31(12), 6325%

Respiratory depression

    • (2023): Lakkad M+, J Cancer Surviv Feb, Online ahead of print (with gabapentinoid)

Adverse effects / adverse reactions

    • (2021): Omoto T+, Biol Pharm Bull 44(5), 627-634 [REVIEW]Geriatric
    • (2021): Paul AK+, Pharmaceuticals (Basel) 14(11), 1091 [REVIEW]
    • (2014): Carter GT+, Phys Med Rehabil Clin N Am 25(2), 457 [REVIEW]

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