Contraindicated in patients with carnitine deficiency or inborn errors of metabolism that may result in clinically significant carnitine deficiency.
Penicillin and cephalosporins share a common beta-lactam structure. People who are allergic to penicillin are approximately 4 times more likely to develop an allergic reaction to a cephalosporin than those people who have no penicillin allergy (from 5–16% of patients allergic to penicillin develop reactions to cephalosporins).