Stavudine
- TRADE NAME: Zerit (Bristol-Myers Squibb)
- INDICATIONS: HIV infection
- SYNONYM: D4T
- CLASS: Antiretroviral, Nucleoside analog reverse transcriptase inhibitor
- HALF-LIFE: 1.44 hours
CLINICALLY IMPORTANT, POTENTIALLY HAZARDOUS INTERACTIONS WITH:
Doxorubicin, Ribavirin, Zidovudine
PREGNANCY CATEGORY: C
LACTIC ACIDOSIS and HEPATOMEGALY with STEATOSIS; PANCREATITIS
See full prescribing information for complete boxed warning.
Please login to see the rest of this drug profile
SKIN.
CARDIOVASCULAR.
CENTRAL NERVOUS SYSTEM.
ENDOCRINE/METABOLIC.
GASTROINTESTINAL/HEPATIC.
HEMATOLOGIC.
NEUROMUSCULAR/SKELETAL.
RENAL.
OTHER.
Click on the DRUG REVIEW ARTICLE tab (above) to see a review of stavudine plus lamivudine in the Taylor & Francis journal Expert Opinion on Drug Safety. (Note that non-subscribers to the journal will only be able to see an abstract of the article.)
Page last updated 07/31/2023
Symbol key
Incidence
- <1%
- 1-5%
- 5-10%
- 10-15%
- 15-20%
- 20-30%
- >30%
Warnings in other populations
- Breast feeding
- Geriatric
- Pediatric