Imipenem/Cilastatin/Relebactam
- TRADE NAME: Recarbrio (MSD)
- INDICATIONS: Patients 18 years of age and older who have limited, or no alternative treatment options, for the treatment of the following infections caused by susceptible gram-negative bacteria: complicated urinary tract infections, including pyelonephritis; complicated intra-abdominal infections
- CLASS: Antibiotic, Antibiotic; carbapenem (imipenem), Antimicrobial, Beta-lactamase inhibitor (relebactam), Renal dehydropeptidase inhibitor (cilastatin)
- HALF-LIFE: 1 hour (imipenem); 1.2 hours (relebactam); 1 hour (cilastatin)
FDA APPROVAL DATE: 07/16/2019
CLINICALLY IMPORTANT, POTENTIALLY HAZARDOUS INTERACTIONS WITH:PREGNANCY CATEGORY: N/A
Insufficient human data to establish whether there is a drug-associated risk for major birth defects, miscarriage, or adverse maternal or fetal outcomes with imipenem, cilastatin, or relebactam in pregnant women.
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CARDIOVASCULAR.
CENTRAL NERVOUS SYSTEM.
ENDOCRINE/METABOLIC.
GASTROINTESTINAL/HEPATIC.
HEMATOLOGIC.
LOCAL.
Page last updated 08/01/2022
Symbol key
Incidence 
- <1%
- 1-5%
- 5-10%
- 10-15%
- 15-20%
- 20-30%
- >30%
Warnings in other populations 
- Breast feeding
- Geriatric
- Pediatric