Glucarpidase
- TRADE NAME: Voraxaze (BTG)
- INDICATIONS: Treatment of toxic plasma methotrexate concentrations in patients with delayed methotrexate clearance due to impaired renal function
- SYNONYM: carboxypeptidase G2; CPG2
- CLASS: Enzyme
- HALF-LIFE: 6 hours
CLINICALLY IMPORTANT, POTENTIALLY HAZARDOUS INTERACTIONS WITH:
Leucovorin, Reduced folates and folate antimetabolites
PREGNANCY CATEGORY: C
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SKIN.
MUCOSAL.
CARDIOVASCULAR.
CENTRAL NERVOUS SYSTEM.
GASTROINTESTINAL/HEPATIC.
OCULAR.
Page last updated 07/31/2023
Symbol key
Incidence
- <1%
- 1-5%
- 5-10%
- 10-15%
- 15-20%
- 20-30%
- >30%
Warnings in other populations
- Breast feeding
- Geriatric
- Pediatric