• TRADE NAME: Voraxaze (BTG)
  • INDICATIONS: Treatment of toxic plasma methotrexate concentrations in patients with delayed methotrexate clearance due to impaired renal function
  • SYNONYM: carboxypeptidase G2; CPG2
  • CLASS: Enzyme
  • HALF-LIFE: 6 hours
  • CLINICALLY IMPORTANT, POTENTIALLY HAZARDOUS INTERACTIONS WITH:
    Leucovorin, Reduced folates and folate antimetabolites

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Page last updated 07/31/2023

Symbol key

Incidence

<1% 1‑5% 5‑10% 10‑15% 15‑20% 20‑30% >30%

Seriousness

Hospitalization possible
Life threatening
Fatal

Warnings in other populations

BreastfeedingBreast feeding

GeriatricGeriatric

PediatricPediatric