As an antidote, it is difficult to differentiate side effects due to the drug from those due to the effects of the poison.
- TRADE NAMES: Antrex; Fusilev (Spectrum); Isovorin (Pfizer); Leucovorin calcium
- INDICATIONS: Antidote for folic acid antagonists, various cancers in combination with other medications
- CLASS: Antidote, Chemotherapy modulating agent, Folate analogue
- HALF-LIFE: 4–8 hours
- CLINICALLY IMPORTANT, POTENTIALLY HAZARDOUS INTERACTIONS WITH:
Trimethoprim
- See adverse reactions attributed to class:
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Page last updated 07/31/2023
