Apomorphine


- TRADE NAMES: Apokyn (Ipsen); Uprima (AbbVie)
- INDICATIONS: Parkinsonism, erectile dysfunction
- CLASS: Dopamine receptor agonist
- HALF-LIFE: 40 minutes
CLINICALLY IMPORTANT, POTENTIALLY HAZARDOUS INTERACTIONS WITH:
5HT3 antagonists, Alcohol, Alosetron, Antihypertensives, Dolasetron, Granisetron, Levomepromazine, Ondansetron, Palonosetron, Risperidone, Vasodilators, Zuclopenthixol
PREGNANCY CATEGORY: C
Apomorphine contains sodium metabisulfite which is capable of causing anaphylactoid reactions in patients with sulfite allergy.
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SKIN.
MUCOSAL.
CARDIOVASCULAR.
CENTRAL NERVOUS SYSTEM.
GASTROINTESTINAL/HEPATIC.
GENITOURINARY.
LOCAL.
NEUROMUSCULAR/SKELETAL.
Page last updated 07/31/2023
Symbol key
Incidence 
- <1%
- 1-5%
- 5-10%
- 10-15%
- 15-20%
- 20-30%
- >30%
Warnings in other populations 
- Breast feeding
- Geriatric
- Pediatric