| Reaction | |
|---|
| Abnormal dreams (66) | |
| Acute disseminated encephalomyelopathy (4) | |
| Ageusia (taste loss) / taste disorder (57) | |
| Aggression (includes anger) (45) | |
| Agitation (142) | |
| Akathisia (57) | |
| Akinetic mutism / mutism (2) | |
| Allodynia (3) | |
| Altered mental status (8) | |
| Amnesia (82) | |
| Amyloid-related imaging abnormalities (ARIA) (1) | |
| Amyotrophic lateral sclerosis (2) | |
| Anorexia (302) | |
| Anorgasmia (12) | |
| Anosmia (smell loss) / smell disorder (see also hyposmia) (19) | |
| Antibiomania / antimicrobial-induced mania (see mania) | |
| Antiphospholipid antibody syndrome (7) | |
| Anxiety (270) | |
| Apathy (1) | |
| Aphasia (13) | |
| Arachnoiditis (6) | |
| Aseptic meningitis (39) | |
| Ataxia / cerebellar ataxia (see ataxia under 'Neuromuscular/Skeletal Adverse Reactions') | |
| Attention disturbances (3) | |
| Balance disorder (18) | |
| Behavioral disturbances / personality changes (26) | |
| Bell's palsy (facial palsy) (4) | |
| Bradykinesia (8) | |
| Bradyphrenia (1) | |
| Brain abscess (1) | |
| Brain atrophy (3) | |
| Brainstem dysgenesis (2) | |
| Carotid artery dissection (1) | |
| Carotidynia / Fay syndrome / Transient Perivascular Inflammation of the Carotid artery (TIPIC) syndrome (2) | |
| Carpal tunnel syndrome (5) | |
| Cataplexy (4) | |
| Catatonia (23) | |
| Central pontine myelinolysis (1) | |
| Cerebellar degeneration (1) | |
| Cerebellar syndrome (5) | |
| Cerebral edema / brain edema (10) | |
| Cerebral hemorrhage (29) | |
| Cerebral infarction (see stroke) | |
| Cerebral ischemia (13) | |
| Cerebral pseudoprogression | |
| Cerebral vasculitis (angiitis) (3) | |
| Cerebral venous sinus thrombosis (includes cavernous sinus thrombosis) (6) | |
| Cerebrovascular accident (26) | |
| Cerebrovascular adverse effect (3) | |
| Chiasmal neuritis (1) | |
| Chills (208) | |
| Chorea (10) | |
| Choreoathetosis (9) | |
| CNS adverse reaction (3) | |
| CNS depression (3) | |
| Cognitive impairment (61) | |
| Cold allodynia / cold sensitivity / cold intolerance (1) | |
| Coma (45) | |
| Coma, myxedema (see myxedema coma under 'Endocrine/Metabolic') | |
| Compulsions / obsessive-compulsive symptoms (29) | |
| Confusion (170) | |
| Cranial neuritis | |
| Cranial neuropathy (3) | |
| Cytokine release syndrome / cytokine storm (9) | |
| Decreased consciousness (22) | |
| Delirium (107) | |
| Delusions (14) | |
| Delusions of parasitosis (6) | |
| Dementia (12) | |
| Demyelinating neuropathy / demyelination (11) | |
| Demyelination | |
| Depersonalization (8) | |
| Depression (319) | |
| Disorientation (22) | |
| Dissociation (psychology) (1) | |
| Disulfiram-like reaction (6) | |
| Dysarthria (41) | |
| Dysesthesia (42) | |
| Dysgeusia (taste perversion) (454) | |
| Dyskinesia (65) | |
| Dysphasia (8) | |
| Dysphemia (see stuttering) | |
| Dysphoria (15) | |
| Emotional lability (18) | |
| Encephalitis (24) | |
| Encephalomyelitis (2) | |
| Encephalopathy (includes hepatic encephalopathy) (116) | |
| Epilepsy (2) | |
| Euphoria / elation (33) | |
| Extrapyramidal symptoms (39) | |
| Fainting (see syncope) | |
| Fall (16) | |
| Fetal hydantoin syndrome (1) | |
| Fever (pyrexia) (includes hyperpyrexia) (616) | |
| Forehead swelling (1) | |
| Gait instability / postural instability (80) | |
| Guillain-Barré syndrome / acute inflammatory demyelinating polyradiculoneuropathy (40) | |
| Hallucinations (159) | |
| Hallucinations, auditory (53) | |
| Hallucinations, olfactory (2) | |
| Hallucinations, visual (see also Charles Bonnet syndrome) (113) | |
| Headache (1097) | |
| Horner's syndrome (1) | |
| Hostility (11) | |
| Hyperactivity (21) | |
| Hyperalgesia (16) | |
| Hyperesthesia (87) | |
| Hyperkinesia (2) | |
| Hypersexuality (7) | |
| Hypersomnia (12) | |
| Hyperthermia (see also pyrexia / hyperpyrexia) (19) | |
| Hypervigilance (1) | |
| Hypoesthesia (numbness) (79) | |
| Hypogeusia (6) | |
| Hypokinesia (11) | |
| Hypomania (14) | |
| Hyporeflexia (3) | |
| Hyposmia / smell disorder (see also anosmia) (5) | |
| Hyposomnia (2) | |
| Hypothermia (21) | |
| Impaired concentration (45) | |
| Impulse control disorder (15) | |
| Incoordination (23) | |
| Insomnia (436) | |
| Intracranial hemorrhage (40) | |
| Intracranial pressure decreased (2) | |
| Intracranial pressure increased (intracranial hypertension) (see also pseudotumor cerebri) (19) | |
| Intraventricular hemorrhage (4) | |
| Irritability (107) | |
| Ischemic injury (1) | |
| Ischemic stroke (14) | |
| Jittery feelings (1) | |
| Leukoencephalopathy / posterior reversible encephalopathy syndrome (PRES) (89) | |
| Loss of consciousness (2) | |
| Malaise (10) | |
| Malignant hyperthermia (7) | |
| Mania (79) | |
| Meige's syndrome (3) | |
| Memory loss/memory impaired (54) | |
| Meningococcal infection (17) | |
| Meningoencephalitis (5) | |
| Meningoradiculitis (1) | |
| Mental status changes (4) | |
| Migraine (56) | |
| Mood changes (78) | |
| Movement disorder (5) | |
| Multiple sclerosis (10) | |
| Myelitis / myeloradiculitis (9) | |
| Myelo-optic-neuropathy (2) | |
| Myelopathy (see also necrotizing myelopathy / necrotic myelopathy / subacute necrotic myelopathy) (2) | |
| Myokymia | |
| Myokymia / twitching (31) | |
| Myxedema coma (see myxedema coma under 'Endocrine/Metabolic') | |
| Narcolepsy (4) | |
| Narcosis (2) | |
| Necrotizing myelopathy / necrotic myelopathy / subacute necrotic myelopathy (2) | |
| Nerve dysfunction (3) | |
| Nervousness (84) | |
| Neuritis (1) | |
| Neuroleptic malignant syndrome (61) | |
| Neurological adverse effect (9) | |
| Neuromyelitis optica (5) | |
| Neuromyopathy (1) | |
| Neuropathy (10) | |
| Neuropsychiatric / neuropsychological adverse effect (23) | |
| Neurotoxicity (324) | |
| Nightmares (41) | |
| Noctambulism (see somnambulism) | |
| Notalgia paresthetica (1) | |
| Numbness (see hypoesthesia) | |
| Opsoclonus-myoclonus-ataxia syndrome (2) | |
| Orbitocranial inflammation (1) | |
| Oro-bucco-lingual dyskinesia / masticatory dyskinesia (see tardive syndrome / tardive dyskinesia) | |
| Othello syndrome (3) | |
| Pain (294) | |
| Palinopsia / visual perseveration (4) | |
| Panic attack (20) | |
| Paralysis / paraplegia (23) | |
| Paraneoplastic neurological syndromes (3) | |
| Paranoia (27) | |
| Parasomnia (see the sleep-related adverse reactions) | |
| Paresis (8) | |
| Paresthesias (487) | |
| Parkinsonism (92) | |
| Parosmia (43) | |
| Parsonage-Turner syndrome (PTS) (brachial plexopathy; neuralgic amyotrophy) (5) | |
| Pavor nocturnus (1) | |
| Perioral paresthesias (5) | |
| Peripheral neuropathy (157) | |
| Periventricular leukomalacia (2) | |
| Posterior reversible encephalopathy syndrome (PRES) (see leukoencephalopathy) | |
| Presyncope (6) | |
| Primary central nervous system lymphoma (PCNSL) (2) | |
| Pseudohallucinations (5) | |
| Pseudoparkinsonism (1) | |
| Pseudotumor cerebri (see also intracranial hypertension) (28) | |
| Psychiatric adverse effect (11) | |
| Psychomotor impairment (8) | |
| Psychosis (146) | |
| Punding (3) | |
| Rabbit syndrome (10) | |
| Restless legs syndrome (43) | |
| Restlessness (67) | |
| Reversible cerebral vasoconstriction syndrome (RCVS) (15) | |
| Rigors (56) | |
| Schizophrenia (13) | |
| Sedation (111) | |
| Seizures (334) | |
| Sensory disturbances (7) | |
| Serotonin syndrome (60) | |
| Sexual fantasies (1) | |
| Shivering (32) | |
| Sleep apnea (3) | |
| Sleep disturbances (56) | |
| Sleep-related disorder (61) | |
| Sleep-related eating disorder (SRED) (7) | |
| Sleepwalking (see somnambulism) | |
| Slurred speech (9) | |
| Somnambulism (sleepwalking; noctambulism) (18) | |
| Somnolence (drowsiness) (364) | |
| Speech disorder (17) | |
| Spinal cord compression (2) | |
| Spinal cord infarction (1) | |
| Spinal shock | |
| Status epilepticus (41) | |
| Status gelasticus (3) | |
| Stroke / cerebral infarction (81) | |
| Stupor (7) | |
| Stuttering (dysphemia) / stammering (20) | |
| Subarachnoid hemorrhage (10) | |
| Subdural hemorrhage (12) | |
| Suicidal ideation (110) | |
| Syncope / fainting (181) | |
| Tardive seizure (1) | |
| Tardive syndrome / tardive dyskinesia (36) | |
| Tic disorder (33) | |
| Tourette's syndrome (1) | |
| Trembling (17) | |
| Tremor (287) | |
| Trichotillomania (hair-pulling disorder) (6) | |
| Tumor pain (2) | |
| Vertigo / dizziness (827) | |
| Warm feeling (includes feeling hot) (18) | |
| Yawning (12) | |
