Litts Drug Eruption & Reaction Database - Presented by CRC Press

The most comprehensive database on adverse drug reactions for our profession.David Adams MD


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Drugs belonging to  restart save

class – Poly (ADP-ribose) polymerase (PARP) inhibitor – 4 items found

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Niraparib

Olaparib

Rucaparib

Talazoparib


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Adverse reactions attributed to entire drug class 'Poly (ADP-ribose) polymerase (PARP) inhibitor'

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Cardiovascular adverse effect (includes major adverse cardiovascular events (MACE))

    • (2023): Palazzo A+, ESMO Open Mar, Online ahead of print5% [REVIEW]

Gastrointestinal adverse reaction

    • (2020): Hao J+, Crit Rev Oncol Hematol Nov, Online ahead of print [REVIEW]

Anemia

    • (2023): Maiorano BA+, Target Oncol Nov, Online ahead of print [REVIEW] (association)
    • (2021): Zeng J+, Zhonghua Fu Chan Ke Za Zhi (Chinese) 56(6), 401-40740%

Hematological adverse effect

    • (2024): Dai MF+, Expert Rev Anticancer Ther May, Online ahead of print [REVIEW] (pharmacovigilance / pharmacoepidemiology)
    • (2021): Liu X+, Front Oncol Oct (e-Collection) [REVIEW]
    • (2021): Zhang M+, J Cancer Res Ther 17(7), 1672-1678 [REVIEW]
    • (2020): Hao J+, Crit Rev Oncol Hematol Nov, Online ahead of print [REVIEW]
    • (2020): Jiang Y+, Front Oncol Jul (e-Collection) [REVIEW]

Myelodysplastic syndrome

    • (2020): Morice PM+, Lancet Haematol Dec, Online ahead of print [REVIEW]

Myeloid leukemia

    • (2020): Morice PM+, Lancet Haematol Dec, Online ahead of print [REVIEW]

Neutropenia (neutrophils decreased)

    • (2023): Maiorano BA+, Target Oncol Nov, Online ahead of print [REVIEW] (association)

Thrombocytopenia / platelets decreased

    • (2023): Maiorano BA+, Target Oncol Nov, Online ahead of print [REVIEW] (association)

Adverse effects / adverse reactions

    • (2024): Uekusa R+, Sci Rep Jun, Online ahead of print (181 patients with ovarian cancer who received olaparib or niraparib)
    • (2023): Cecere SC+, Expert Opin Drug Saf Sep, Online ahead of print
    • (2023): Society Of Obstetrics And Gynecology OZMA+, Zhejiang Da Xue Xue Bao Yi Xue Ban 51(6), 765-774 [REVIEW]
    • (2022): Luo J+, Front Oncol Jun (e-Collection) [REVIEW]
    • (2022): Yamaoka K+, Life (Basel) 12(9), 1355 [REVIEW]
    • (2021): Jesus M+, Expert Opin Drug Saf Oct, Online ahead of print [REVIEW]
    • (2020): Shao F+, Biosci Rep Feb, Epub ahead of print55% (grade 3–4 (serious, 26%)) [REVIEW]
    • (2020): Xu Y+, Front Oncol Feb (e-Collection) [REVIEW]
    • (2020): Yang Y+, World J Surg Oncol 18(1), 151 [REVIEW]

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