• SCIENTIFIC NAMES: N-(aminoiminomethyl)-N methyl glycine; N-amidinosarcosine
  • INDICATIONS: Improve exercise performance, increase muscle mass, heart failure, neuromuscular disease, cholesterol-lowering, amyotrophic lateral sclerosis, rheumatoid arthritis, cardiac surgery (IV)
  • CLASS: Food supplement
  • HALF-LIFE: N/A
  • CLINICALLY IMPORTANT, POTENTIALLY HAZARDOUS INTERACTIONS WITH:
    None known

Creatine is found primarily in skeletal muscle (95%), also in heart, brain, testes and other tissues. The body synthesizes 1–2 grams of creatine a day.

Creatine use is widespread among amateur and professional athletes. Americans use more than 4 million kilograms of creatine each year.

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Page last updated 07/31/2023

Symbol key

Incidence

<1% 1‑5% 5‑10% 10‑15% 15‑20% 20‑30% >30%

Seriousness

Hospitalization possible
Life threatening
Fatal

Warnings in other populations

BreastfeedingBreast feeding

GeriatricGeriatric

PediatricPediatric