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- TRADE NAMES: Apo-Bisoprolol; Cardicor (Merck Serono); Concor (Merck Serono); Emcor (Merck Serono); Monocor; Zebeta (Barr); Ziac (Barr)
- INDICATIONS: Hypertension
- CLASS: Beta adrenergic blocker, Beta blocker
- HALF-LIFE: 9–12 hours
- CLINICALLY IMPORTANT, POTENTIALLY HAZARDOUS INTERACTIONS WITH:
Diltiazem, Disopyramide, Guanethidine, Reserpine, Rifampin, Verapamil
- See adverse reactions attributed to class:
Ziac is bisoprolol and hydrochlorothiazide.
Hydrochlorothiazide is a sulfonamide and can be absorbed systemically. Sulfonamides can produce severe, possibly fatal, reactions such as toxic epidermal necrolysis and Stevens-Johnson syndrome.
Contra-indicated in patients with cardiogenic shock, overt cardiac failure, second or third degree AV block, and marked sinus bradycardia.
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Page last updated 01/04/2025
