Bisoprolol

BreastfeedingPediatric
  • TRADE NAMES: Apo-Bisoprolol; Cardicor (Merck Serono); Concor (Merck Serono); Emcor (Merck Serono); Monocor; Zebeta (Barr); Ziac (Barr)
  • INDICATIONS: Hypertension
  • CLASS: Beta adrenergic blocker, Beta blocker
  • HALF-LIFE: 9–12 hours
CLINICALLY IMPORTANT, POTENTIALLY HAZARDOUS INTERACTIONS WITH:

Diltiazem, Disopyramide, Guanethidine, Reserpine, Rifampin, Verapamil

PREGNANCY CATEGORY: C

Ziac is bisoprolol and hydrochlorothiazide.

Hydrochlorothiazide is a sulfonamide and can be absorbed systemically. Sulfonamides can produce severe, possibly fatal, reactions such as toxic epidermal necrolysis and Stevens-Johnson syndrome.

Contra-indicated in patients with cardiogenic shock, overt cardiac failure, second or third degree AV block, and marked sinus bradycardia.

Our database has 26 adverse reactions for this drug across the following areas

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SKIN.
MUCOSAL.
CARDIOVASCULAR.
CENTRAL NERVOUS SYSTEM.
ENDOCRINE/METABOLIC.
GASTROINTESTINAL/HEPATIC.
GENITOURINARY.
HEMATOLOGIC.
NEUROMUSCULAR/SKELETAL.
OTHER.


Page last updated 08/01/2022

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Incidence info

  • <1%
  • 1-5%
  • 5-10%
  • 10-15%
  • 15-20%
  • 20-30%
  • >30%

Seriousness info

  • Hospitalization possible
  • Life threatening
  • Fatal

Warnings in other populations info

  • Breast feeding
  • Geriatric
  • Pediatric
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