Inclisiran
- TRADE NAME: Leqvio (Novartis)
- INDICATIONS: Adjunct to diet and statin therapy for the treatment of adults with heterozygous familial hypercholesterolemia or clinical atherosclerotic cardiovascular disease.
- CLASS: Small interfering RNA (siRNA)
- HALF-LIFE: Approximately 9 hours
FDA APPROVAL DATE: 12/22/2021
CLINICALLY IMPORTANT, POTENTIALLY HAZARDOUS INTERACTIONS WITH:None known
Discontinue inclisiran when pregnancy is recognized.
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GASTROINTESTINAL/HEPATIC.
GENITOURINARY.
LOCAL.
NEUROMUSCULAR/SKELETAL.
RESPIRATORY.
OTHER.
Page last updated 03/08/2023
Symbol key
Incidence 
- <1%
- 1-5%
- 5-10%
- 10-15%
- 15-20%
- 20-30%
- >30%
Warnings in other populations 
- Breast feeding
- Geriatric
- Pediatric