• TRADE NAME: Leqvio (Novartis)
  • INDICATIONS: Adjunct to diet and statin therapy for the treatment of adults with heterozygous familial hypercholesterolemia or clinical atherosclerotic cardiovascular disease.
  • CLASS: Small interfering RNA (siRNA)
  • HALF-LIFE: Approximately 9 hours
  • FDA APPROVAL DATE: 12/22/2021
  • CLINICALLY IMPORTANT, POTENTIALLY HAZARDOUS INTERACTIONS WITH:
    None known
  • PREGNANCY: Discontinue inclisiran when pregnancy is recognized.

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Page last updated 07/31/2023

Symbol key

Incidence

<1% 1‑5% 5‑10% 10‑15% 15‑20% 20‑30% >30%

Seriousness

Hospitalization possible
Life threatening
Fatal

Warnings in other populations

BreastfeedingBreast feeding

GeriatricGeriatric

PediatricPediatric