Melphalan flufenamide comment watch save

  • TRADE NAME: Pepaxto (Oncopeptides)
  • INDICATIONS: Relapsed or refractory multiple myeloma (in combination with dexamethasone)
  • SYNONYM: Melflufen
  • CLASS: Alkylating agent
  • HALF-LIFE: 70 minutes
  • FDA APPROVAL DATE: 02/26/2021
  • CLINICALLY IMPORTANT, POTENTIALLY HAZARDOUS INTERACTIONS WITH:
    None known
  • PREGNANCY: Based on its mechanism of action, melphalan flufenamide can cause fetal harm when administered to a pregnant woman. Advise pregnant women of the potential risk to a fetus

Prodrug of melphalan

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Page last updated 07/31/2023

Symbol key

Incidence

<1% 1‑5% 5‑10% 10‑15% 15‑20% 20‑30% >30%

Seriousness

Hospitalization possible
Life threatening
Fatal

Warnings in other populations

BreastfeedingBreast feeding

GeriatricGeriatric

PediatricPediatric