Scopolamine
- TRADE NAMES: Isopto Hyoscine Ophthalmic; Kwells (Bayer); Scopace; Scopoderm-TTS (Novartis); Transderm-Scop Patch (Novartis); Transdermal-V
- INDICATIONS: Nausea and vomiting, excess salivation
- SYNONYM: hyoscine
- CLASS: Anticholinergic, Antiemetic, Muscarinic antagonist
- HALF-LIFE: 8 hours
Anticholinergics, Arbutamine
PREGNANCY CATEGORY: C
The UK Medicines and Healthcare products Regulatory Agency: Safety update (July 2023)
Hyoscine hydrobromide patches (Scopoderm 1.5mg Patch or Scopoderm TTS Patch): risk of anticholinergic side effects, including hyperthermia
There have been a small number of reports of serious and life-threatening anticholinergic side effects associated with hyoscine hydrobromide patches, particularly when used outside the licence. Healthcare professionals, patients, parents and carers should be aware of the signs and symptoms of serious side effects and the need to seek medical help if they occur.
Systemic adverse effects have been reported following ophthalmic administration.
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Page last updated 08/05/2023
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Incidence
- <1%
- 1-5%
- 5-10%
- 10-15%
- 15-20%
- 20-30%
- >30%
Warnings in other populations
- Breast feeding
- Geriatric
- Pediatric