Rosiglitazone drug interactions | Litt's Drug Eruption and Reaction Database

Rosiglitazone comment watch save

TRADE NAMES: Avandamet (GSK); Avandaryl (GSK); Avandia (GSK)
INDICATIONS: Type II diabetes
CLASS: Antidiabetic, Hypoglycemic (antihyperglycemic) agent, Thiazolidinedione
HALF-LIFE: 3–4 hours

CLINICALLY IMPORTANT, POTENTIALLY HAZARDOUS INTERACTIONS WITH:
CYP2C8 inhibitors and inducers, Gemfibrozil, Grapefruit Juice, Letermovir, Paclitaxel, Rifampin, Teriflunomide

See adverse reactions attributed to class:
Antidiabetic
Thiazolidinedione

Thiazolidinediones, including rosiglitazone, cause or exacerbate congestive heart failure in some patients.

Contra-indicated in patients with established NYHA Class III or IV heart failure.

Avandaryl is rosiglitazone and glimepiride; Avandamet is rosiglitazone and metformin.

CONGESTIVE HEART FAILURE

See full prescribing information for complete boxed warning.

Please login to view the rest of this drug profile.

Page last updated 07/31/2023

Litt's app available free to subscribers

Search drug eruptions and reactions data anytime, anywhere

Symbol key

Incidence

<1% 1‑5% 5‑10% 10‑15% 15‑20% 20‑30% >30%

Seriousness

Hospitalization possible
Life threatening
Fatal

Warnings in other populations

Breast feeding

Geriatric

Pediatric