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  • TRADE NAME: Tavalisse (Rigel)
  • INDICATIONS: Thrombocytopenia in adult patients with chronic immune thrombocytopenia who have had an insufficient response to a previous treatment
  • CLASS: Spleen tyrosine kinase (Syk) inhibitor
  • HALF-LIFE: ~15 hours
  • FDA APPROVAL DATE: 04/17/2018
  • CLINICALLY IMPORTANT, POTENTIALLY HAZARDOUS INTERACTIONS WITH:
    Strong CYP3A4 inhibitors or inducers
  • PREGNANCY: Based on animal studies, can cause fetal harm

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DRUG REVIEW ARTICLE

Click on the DRUG REVIEW ARTICLE tab (above) to see a review of fostamatinib in the Taylor & Francis journal Expert Opinion on Drug Safety.

(Note that non-subscribers to the journal will only be able to see an abstract of the article.)

Page last updated 08/20/2025

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Incidence - Help

<1% 1‑5% 5‑10% 10‑15% 15‑20% 20‑30% >30%

Seriousness - Help

Hospitalization possible
Life threatening
Fatal

Warnings in other populations - Help

BreastfeedingBreast feeding

GeriatricGeriatric

PediatricPediatric