Metolazone comment watch save

  • TRADE NAMES: Barolyn; Diondel; Metenix 5; Normelan; Xuret; Zaroxolyn (Celltech)
  • INDICATIONS: Hypertension, edema
  • CLASS: Diuretic, thiazide
  • HALF-LIFE: 6–20 hours
  • CLINICALLY IMPORTANT, POTENTIALLY HAZARDOUS INTERACTIONS WITH:
    Digoxin, Lithium

Metolazone is a sulfonamide and can be absorbed systemically. Sulfonamides can produce severe, possibly fatal, reactions such as toxic epidermal necrolysis and Stevens-Johnson syndrome.

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Page last updated 07/31/2023

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Incidence

<1% 1‑5% 5‑10% 10‑15% 15‑20% 20‑30% >30%

Seriousness

Hospitalization possible
Life threatening
Fatal

Warnings in other populations

BreastfeedingBreast feeding

GeriatricGeriatric

PediatricPediatric

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