Telotristat Ethyl comment watch save
BreastfeedingPediatric

  • TRADE NAME: Xermelo (Lexicon)
  • INDICATIONS: Carcinoid syndrome diarrhea in combination with somatostatin analog (SSA) therapy for adults inadequately controlled by SSA therapy
  • CLASS: Tryptophan hydroxylase inhibitor
  • HALF-LIFE: <1 hour
  • FDA APPROVAL DATE: 02/28/2017
  • CLINICALLY IMPORTANT, POTENTIALLY HAZARDOUS INTERACTIONS WITH:
    CYP3A4 substrates
  • PREGNANCY: No available data to inform drug-associated risk

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Page last updated 08/20/2025

Symbol key

Incidence - Help

<1% 1‑5% 5‑10% 10‑15% 15‑20% 20‑30% >30%

Seriousness - Help

Hospitalization possible
Life threatening
Fatal

Warnings in other populations - Help

BreastfeedingBreast feeding

GeriatricGeriatric

PediatricPediatric