• TRADE NAME: Savaysa (Daiichi Sankyo)
  • INDICATIONS: Reduce the risk of stroke and systemic embolism in patients with nonvalvular atrial fibrillation; treatment of deep vein thrombosis and pulmonary embolism
  • CLASS: Direct factor Xa inhibitor
  • HALF-LIFE: 10–14 hours
  • FDA APPROVAL DATE: 01/08/2015
  • CLINICALLY IMPORTANT, POTENTIALLY HAZARDOUS INTERACTIONS WITH:
    Anticoagulants, Rifampin

Contra-indicated in patients with active pathological bleeding.

REDUCED EFFICACY IN NONVALVULAR ATRIAL FIBRILLATION PATIENTS WITH CRCL>95ml/min, ISCHEMIC EVENTS ON PREMATURE DISCONTINUATION and SPINAL/EPIDURAL HEMATOMA

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    DRUG REVIEW ARTICLE

    Click on the DRUG REVIEW ARTICLE tab (above) to see a review of edoxaban in the Taylor & Francis journal Expert Opinion on Drug Safety.

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Page last updated 10/26/2024

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Incidence

<1% 1‑5% 5‑10% 10‑15% 15‑20% 20‑30% >30%

Seriousness

Hospitalization possible
Life threatening
Fatal

Warnings in other populations

BreastfeedingBreast feeding

GeriatricGeriatric

PediatricPediatric