Summary for Hydroflumethiazide

  • Trade Names: Diademil; Hydravern; Hydrenox; Leodrine; Rivosil; Rontyl
  • Indications: Hypertension, edema
  • Class: Diuretic, thiazide
  • Half-life: 12–24 hours
  • Clinically important, potentially hazardous interactions with:
    Digoxin, Lithium

Hydroflumethiazide is a sulfonamide and can be absorbed systemically. Sulfonamides can produce severe, possibly fatal, reactions such as toxic epidermal necrolysis and Stevens-Johnson syndrome

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Page last updated 08/20/2025

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Incidence - Help

<1% 1‑5% 5‑10% 10‑15% 15‑20% 20‑30% >30%

Seriousness - Help

Hospitalization possible
Life threatening
Fatal

Warnings in other populations - Help

BreastfeedingBreast feeding

GeriatricGeriatric

PediatricPediatric

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