Summary for Prothrombin Complex Concentrate (Human)


BreastfeedingPediatric
  • Trade Name: Kcentra (CSL Behring)
  • Indications: Urgent reversal of acquired coagulation factor deficiency induced by vitamin K antagonist therapy in adult patients with acute major bleeding
  • Synonym: PCC
  • Class: Coagulant
  • Half-life: 4–60 hours
  • Clinically important, potentially hazardous interactions with:
    None known

ARTERIAL AND VENOUS THROMBOEMBOLIC COMPLICATIONS

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Page last updated 08/20/2025

Symbol key

Incidence - Help

<1% 1‑5% 5‑10% 10‑15% 15‑20% 20‑30% >30%

Seriousness - Help

Hospitalization possible
Life threatening
Fatal

Warnings in other populations - Help

BreastfeedingBreast feeding

GeriatricGeriatric

PediatricPediatric