Contra-indicated in patients with regional enteritis, ulcerative colitis, or history of antibiotic-associated colitis.
Exposure to sunlight, sunlamps, and weather extremes should be avoided during the use of clindamycin/tretinoin gel.
The reactions listed below are specific to the clindamycin/tretinoin combination product. See also profiles of clindamycin and tretinoin for reactions associated with the individual products.