Clindamycin/Tretinoin
- TRADE NAMES: Velac; Veltin (Astellas, Stiefel); Ziana (Medicis)
- INDICATIONS: Acne vulgaris (topical use only)
- CLASS: Antibiotic, Antibiotic; lincosamide, Antimicrobial, Retinoid
- HALF-LIFE: N/A
CLINICALLY IMPORTANT, POTENTIALLY HAZARDOUS INTERACTIONS WITH:
Erythromycin, Neuromuscular blocking agents, Other topical medications with a skin drying effect
PREGNANCY CATEGORY: C
Contra-indicated in patients with regional enteritis, ulcerative colitis, or history of antibiotic-associated colitis.
Exposure to sunlight, sunlamps, and weather extremes should be avoided during the use of clindamycin/tretinoin gel.
The reactions listed below are specific to the clindamycin/tretinoin combination product. See also profiles of clindamycin and tretinoin for reactions associated with the individual products.
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SKIN.
GASTROINTESTINAL/HEPATIC.
LOCAL.
OTHER.
Page last updated 07/31/2023
Symbol key
Incidence 
- <1%
- 1-5%
- 5-10%
- 10-15%
- 15-20%
- 20-30%
- >30%
Seriousness
- Hospitalization possible
- Life threatening
- Fatal
Warnings in other populations
- Breast feeding
- Geriatric
- Pediatric
