Cryopyrin-associated periodic syndromes (CAPS) are characterized by life-long, recurrent symptoms of rash, fever/chills, joint pain, eye redness/pain, and fatigue. Intermittent, disruptive exacerbations or flares can be triggered at any time by exposure to cooling temperatures, stress, exercise, or other unknown stimuli.
- TRADE NAME: Arcalyst (Regeneron)
- INDICATIONS: Cryopyrin-associated periodic syndromes (CAPS) including familial cold autoinflammatory syndrome (FCAS), Muckle-Wells syndrome (MWS)
- CLASS: Fusion protein, Interleukin-1 inhibitor
- HALF-LIFE: N/A
- CLINICALLY IMPORTANT, POTENTIALLY HAZARDOUS INTERACTIONS WITH:
anti-TNF agents, Lenalidomide, live vaccines, Natalizumab
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Page last updated 07/31/2023
